onslowsmom avatar image

Mast Cell Tumors - Looking for people with experience/information :(

Onslow has one on the top of his front leg, we had the vet aspirate it last night.  =(  Trying not to flip out about it, I understand they are common. 

Have you ever had a lump come with allergies and then go away?  Did you have to remove it?  Any recurrences after that?  What course of treatment did you use?  Any information is appreciated.  I have a lot of research to do. 

He is due for his rabies and I am really super hesitant to give him the shots anymore.  Any thoughts on that?

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onslowsmom's picture

Oh and I should also mention

that he has been on Pred before and did not respond well to it, at all.  It gave him super liquid exploding diarreah (sorry for the yucky description).  So I'm not sure he will be able to take that =(

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Shannon and Winston's picture

oh no Onslow!

I'm sorry Lisa!  I don't have any experience but please know I'm sending good thoughts and prayers out for you and Onslow!  I really hope you can find some answers here.

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Shannon and Winston :)

My swimming bully buddy!

My swimming bully buddy!

onslowsmom's picture

Thank you Shannon.

sending a big ole smooch to my man Winston.  Hope you guys are doing well.  =)

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Monica-Maude-Gus's picture

No experience with mast cell tumors

But I had to let you know that all of you are in my prayers and thoughts, especially Mr. O.  He is such a special little man to all of us.

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Monica, Maude and Gus

onslowsmom's picture

Thank you Monica

that means a lot to me <3  Hope you are doing well.  I have missed chatting with you all. 

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Kathy Chester Newman and Jessa's picture

Ollie had a mast cell tumor about two years ago...

He had an ugly, red lump on his belly and a little wart on his neck that we were treating with cortisone cream.  The vet wanted to remove the belly lump and at the same time decided to remove the wart.  Well, the lump was just an infection, but the wart was a mast cell.  Ollie had to have another surgery to make sure they had clean margins.  He had a huge scar, but it's healed over nicely.  He didn't have chemo, the vet was confident he got it all and he's been fine ever since.  They explained to me that mast cells in dogs are like skin cancer in humans, so we limit his sunbathing and watch for new ones, so far so good.  Sending good thoughts for your boy.  If you have any questions, let me know. 

onslowsmom's picture

Thank you for your response Kathy

I am sorry that you have so much experience with Cancer.  :(  But I'm glad that Ollie is ok.  His doesn't look like a wart at all.  Its like a hard pea sized lump under the skin.  My heart sank when they told me it was mast cell but it seems that alot of them are ok with just the removal (from what I'm reading).  Fingers crossed.  Thanks for sharing your experience with me.  - L

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AmyandSophia's picture

No experience with Mast Cell Tumors.

But one thing...under the skin, is it attached to anything or free moving? I mean, is it right under the skin and attached to something internally so it won't move, or is it able to be moved around and isn't held by muscle, tendon, etc?

If it isn't attached there is a good chance they can just remove the tumor itself and there won't be surrounding affected tissue. I will be praying for you guys.

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Amy and Sophia

onslowsmom's picture

I think its free moving

I'll be home pulling on it later. LOL  Thanks Amy. =)

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AmyandSophia's picture

All I know is...when I have had a question about that...

About free moving as opposed to connected tissue, the answer is positive. Kora has a couple of free moving tumors and so does my big gelding. Vets have said they are a lot better than having a tissue connection issue. Less likely to cause other issues after removal.

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Amy and Sophia

My bully had one mast cell tumor...

on her leg and our vet decided that even though he thought it not a problem he would take a sample and have it biopsied. Thankfully he did as it turned out to be a tumor. He then operated and removed it. He made a fairly wide margin around the tumor and got it all. He told us that if she were able to get through the first year after that with no more appearing she would be fine. He was right. She had the tumor at 7 and lived to be almost 11 when she died of heart problems. Chemo/radiation were never discussed. Hoping you too have a most satisfactory result with your bully.

onslowsmom's picture

Carol

thank you for your response.  Stories like yours put me more at ease, he is 5.  Thank you for that and your well wishes.  =)  I'll keep you all posted about his progress.

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no experience

but just wanted to let you know your post caught my breath and I had tears until I googled the diagnosis and it seems it is the most leading cancer that is cured in dogs : )

Sending Onslow big huge kisses, prayers and healing vibes!

onslowsmom's picture

Thanks Annie

I know my heart sank when they told us last night.  I'm hoping he'll be just fine.  The "c" word is scary no matter what.  Thanks for your support =)

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Deb and MacKenzie and Ester's picture

Mast Cell Tumors

MacKenzie has had a maglignant Mast Cell Tumor, Grade 1 which is a low grade.  My vet opted to remove it with large margins prior to biopsy since it meant only putting him under once.  It is rather alarming how large of an area they actually took and the size of the incision, but it healed nicely and you can't even tell where it was. It was on his forechest close to his right leg.  A friend of mine actually noticed it first and we watched it for a year and it grew so we suspected to could be maglignant and had it removed.

He has also had several tumors on his gums that have needed to be removed but those have been benign.

I was told by several bullie breeders to put him on an antihistamine like Benedryl.  But I never have and has not gotten anymore tumors as of yet.

I hope if it is maglignant it is a low grade.   Give Onslow smooches for me.

onslowsmom's picture

Hi Deb

Thanks for your response.  Onslows is in the same exact spot as MacKenzie's was.  I'm glad to hear that he hasn't had any more problems since, and I appreciate you telling me about him.  Also appreciate you warning me about the size of the incision - so I won't be shocked. 

I hope you are doing well, its been a long time since we have seen each other on line.  Sending smooches back to your guys. 

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Deb and MacKenzie and Ester's picture

You have been MIA :)

I peek in but don't post much anymore. 

Keep us posted on how Onslow does with the surgery if they decide to remove it.  When do you get lab results?  Sending good thoughts you way.

onslowsmom's picture

Guilty

I pop in but haven't been posting much either.  We are going to see if the meds shrink it.  Hes on Simplicef, Hydroxyzine and Ketaconazole for 10 days.  Back to the vet in 2 weeks to reassess.  At that point we will decide if it needs to go or not.  I suppose if it hasn't gone down we will definitely remove it.  I'll keep you all posted.  Thanks again for your support!

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Céline and Angel Stella's picture

Oh no!!

Onslow baby. - what the heck!  I don't like seeing the "t" word in a post about you.

Stella had a tumour (not sure it was mast cell) on her ear several years ago.  Because it was on the ear, we were able to freeze it off using cryosurgery.  That meant she didn't even have to be put under.  They froze the ear area and zapped it right there and then - with mummy whispering sweet nothings.  The thing fell off a few days later (gross!).

Not sure this would work in this case, depending on where it's located.  But you could always inquire about cryo-surgery.  It never came back, by the way.

 

 

onslowsmom's picture

Hi Celine

Ya its on his chest area near the top of his leg right now its just a pea size.  Sorta near his armpit.  We are hoping the antibiotics will get rid of it but if not we'll have it removed.  I'll keep you posted on him.  10 days of antibiotics so I should know what we will do in a few weeks.

BIG SMOOCHES to both of you girls.  I miss you!

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good article on Mast Cell Tumors

This article was given to me by my vet., my 8 year old bullie just had one removed 6 weeks ago.  I discovered the lump on her abdomen took her to have it checked a needle biopsy was done it was a mast cell she was booked for surgery next day and had it removed.  Thank god it was low grade tumor all of the margins were clear.  My vet did administer an antihistamine during surgery and post op I had to give 1 benadryl per day for 7 days.  Since this lump was discovered I have to keep a watchful eye on her sometimes they can get another and sometimes one is all they have I pray for me it's the latter these tumors can be deadly.  Location is the number one issue (ie) inbetween toes, middle of forehead, places that limits the capability of excising all of the tissue outside the margins.  Good Luck

 

 

Mast Cell Tumors in Dogs
BASIC INFORMATION
Description and Causes
These tumors are composed of a white blood cell called a mast
cell . Mast cell tumors (MCTs) are the most common malignant
skin tumor of dogs. The cause is unknown, but a virus that causes
mutations has been proposed, because many dogs with MCTs have
mutations in a specific gene that may be responsible for the creation
and/or progression of MCTs.
MCTs usually develop in middle-aged to older dogs but are
occasionally found in dogs as young as 4 months. They occur
commonly in the boxer, Boston terrier, bull terrier, bullmastiff,
Staffordshire bull terrier, fox terrier, English bulldog, dachshund,
Labrador retriever, golden retriever, beagle, pug, Chinese shar-pei,
Rhodesian ridgeback, and Weimaraner. All MCTs in the dog are
considered potentially malignant.
Clinical Signs
These tumors are generally hairless, red, swollen bumps that vary
in size (less than 1 inch up to several inches). They often occur
on the trunk (body), head, and legs. Sometimes, tumors on the
legs and lips look only like areas of swelling. Rarely, if substances
such as histamine and heparin are released from the tumors all at
once, generalized swelling, poor blood clotting, low blood pressure
(weakness, lethargy), and even death can occur.
Diagnostic Tests
Taking a sample of the tumor with a needle and examining the
material under a microscope (cytology) is often helpful, because
mast cells are unique. The grade or stage of tumor (severity of
malignancy) can be determined only if the tumor is biopsied.
Biopsy can be done in some tumors prior to removal, or the entire
tumor can be removed and submitted for biopsy. MCTs are classified
as stage I, II, or III. Stage III is the worst (most malignant).
Once a diagnosis of MCT is confirmed, other tests are needed to
look for spread (metastasis) of the tumor. Examples include:
• Checking nearby glands (lymph nodes) for mast cells
• Examining blood cells and the bone marrow for mast cells
• Performing an abdominal ultrasound to check the liver, spleen,
and other organs
• Obtaining x-rays of the chest
TREATMENT AND FOLLOW-UP
Treatment Options
Surgery is the most common treatment option and is done early as
possible. If possible, a large area of normal tissue around the tumor
is removed to try and prevent the tumor from coming back. All of
this tissue is examined by the pathologist to determine whether the
MCT has been completely removed.
If complete removal is not possible with surgery, radiation
therapy or chemotherapy may be recommended. These treatments
are used for some stage II and many stage III MCTs. Occasionally,
certain antihistamine medications may be given to control the
problems associated with histamine release.
Follow-up Care
Recheck examinations every 3-4 months are used to monitor the
dog for new bumps and to check for metastasis to regional glands
or internal organs. Laboratory tests (as often as every 1-3 weeks)
are needed to monitor for the side effects of chemotherapy drugs.
Prognosis
Survival rates of dogs are about 83% with stage I tumors, 44%
with stage II tumors, and 6% with stage III tumors. A bad prognosis
is associated with tumors that grow rapidly, are located in deeper
tissues, or cause the skin to be raw or ulcerated and when other
signs are present.

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Debi

onslowsmom's picture

Hi Debi

Thanks for the article. I'm sorry that you are dealing with this too and I will keep you in my good thoughts that there won't be another one for either one of us.  I appreciate you sharing her story with me, best wishes.  - Lisa

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Shannon and Winston's picture

question

When are you supposed to get the results of the test?

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Shannon and Winston :)

My swimming bully buddy!

My swimming bully buddy!

onslowsmom's picture

Hi Shannon

well he is having an allergy flare up (pyoderma) right now and from what I am understanding these tumors can be the histamines coming out of their skin.  So for now we have him on antibiotics to see if the lump shrinks.  If it does we are all good.  If not we will then consider removing it.  Once it is removed they will biopsy it and then we will know what stage it is. 

Right now I am hoping for the shrinkage!  We go back to the vet to reassess in 2 weeks. 

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Shannon and Winston's picture

I think this is the first I've ever prayed for shrinkage!

:)

Seriously, I do really hope the thing goes away on its own!!

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Shannon and Winston :)

My swimming bully buddy!

My swimming bully buddy!

onslowsmom's picture

ah hahahahaha

Me too.  Shrink baby shrink!  =)

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Céline and Angel Stella's picture

Oops, my response is burried in Deb's

Don't know if it will help, but it might be worth inquiring about!

Wow, sorry to hear this, Lisa

Good thoughts that it's low grade. 

No experience with these tumors, but I know that they have to excise a pretty large area around the tumor to get good margins. 

Hugs to Onslow!

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Olivia

onslowsmom's picture

Well Hello

Olivia!  I'm happy to see you!  Thanks for the good thoughts.  Hope you are doing well.  =)

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HOLLAND75's picture

No experience, but wishing Onslow the speedy recovery

Thinking of you guys

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Silverback's Immaculate Interception, "James"

onslowsmom's picture

Thanks!

=)

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