Bentley's Cystine stones
Submitted by HJWhalen on May 13, 2010 - 9:04pmHi everyone I just wanted to update everyone on Bentley because people have been asking how he is. Well it's been a year struggle. Having an inherited genetic disease has been no fun for us or our poor guy:( we took him to the vet on Sat. and blood in the urine and Crystals again plus bacteria. We are doing a Cystine level test again to see if it is still high. The last time he was tested it was +4 which is the highest. Dr. Navin tested him again to see if the UD is working it takes about a month for results. I just wish we had our old healthy boy back. We have been spending money as if it really grew off a tree. I'm writing this so others out there don't suffer pain like we are. If you're Bulldog shows signs get them tested. If you know it is in your line do some research have you're males at least tested. This is a hard disease to catch but when it does show up red flags are DO NOT BREED! This is so painful it makes me upset just to write about him. We lost our first Bulldog to Cancer now this Inherited disease is crippling his life and ours. Depending on if the Crystals are Cystine and a stone forms again he will be nurtured and another hole put in to maybe help him this would be his 2nd surgery, he has had so may catheters we have lost tack . The vet wants to do it all at once when he is under. I'll post more when we have more news. Thanks to everyone for being so kind and thinking of Bentley. Holly, Jeremy, Bentley,and Bella
Canine Hyperuricosuria
This is a uric acid based stone which is inherited and Bulldogs are one of the more common breeds affected by it. There is a DNA test out there to check for this cause of bladder and kidney stones. You can get information and order kits from UC-Davis here. It you are a breeder, it's a small price [$65] to know if your dogs are affected, carriers or clear of this genetic mutation. You can then plan your breedings accordingly -- because it's a simple autosomal recessive gene you can breed it out of your line if it's there by breeding any affecteds to only clears and carriers to clears. We've tested our stock and can comfortably tell our puppy buyers that their puppy's parents have been tested and are clear.
Beth Handrick
Wimsey Bulldogs
Beth
Wimsey Bulldogs
This is a Cystine stone different then Hyperuricosuria
This is a Cystine stone different than uric acid stones (Hyperuricosuria)
At this time, there is a DNA test available for cystinuria only in Newfoundlands and Labrador Retrievers
Not Bulldogs.
Cystinuria is a genetic defect in the kidney tubules. Normal kidneys filter the amino acid cystine and do not allow it to go into the urine. In dogs with cystinuria, this filtering action fails, and cystine passes into the urine, where it can form crystals and/or stones (uroliths). If stones form, they can block the urethra and obstruct urinary flow, especially in males.
This is what you are talking about: When the stones are made up of uric acid, they are called urate stones. These stones can also be found in the kidneys and in the tubes connecting the kidneys to the animal's bladder (ureters).
I did not breed him............ Bentley will be neutered no breeding will ever be done and the surgery will be done. You must test you're dogs for this, the Cystine test is $120.00 per Dog/Bitch we have done it twice.
Thanks for the intrest!
Cystinuria in the Newfoundland
Newfoundland Cystinuria
Cystinuria in the Newfoundland dog is indicated by the presence of cystine stones in the kidney, bladder or ureter. Failure by the kidneys to reabsorb amino acids results in the formation of these stones.
It is an autosomal recessive disease thus an animal affected with the disease has inherited one copy of the mutation from each parent.
Inheriting only one copy from one parent yields carrier status. The disease is not present but the animal must be bred carefully to prevent creating affected offspring.
Clear The disease in not present in your dog. When used for breeding, a Clear dog will not pass on the disease gene. Carrier One copy of the disease gene is present in your dog, but it will not exhibit disease symptoms. Carriers will not have related medical problems, but will pass on the disease gene 50% of the time. Affected This finding indicates that two copies of the disease gene are present in the dog. Unfortunately, the dog will be medically affected by the disease.I Know
that it is a different type of stone and issue. I was wanting to point out that for the uric acid stones there is a DNA test available for Bulldogs and that we should make use of it if you have had a dog with stone issues. I'm hoping that if enough of us make use of the DNA for the uric acid stones that we can generate enough interest for the researchers to look at adding Bulldogs to the cystinuira DNA test. We may be asked to provide blood samples for clears and affecteds some time down the road to help push this forward. Any type of stones that are hereditary [and I believe most are] need to be addressed using whatever tools we have available to help prevent producing more heartbreak for owners and discomfort and suffering for their dogs.
May the surgery put an end to Bentley's problems.
Beth
Beth
Wimsey Bulldogs
glad bentley is doing at least ok,,,,,
my heart goes out to you.....i have several health issues with wilson and these are breed inherited problems.....but their and as seriouse as you....i will add bently to our prayer list for pets at my church and have a prayer said every friday for him.....i hope all the best....i can feel for you as i some times watch wilson and my heart breaks....
best of luck and keep us posted please...
Than you:)
Thank you, give you're bully a big kiss from us:) Thanks Judy
also thanks for the education.....
i never knew about this....and i think it is so important for people to speak up and say this is a problem....but more important you told us what is needed.....more breeders have to test...and test everything....their are never mever enough test...for healthy dogs....
again thank you for speaking about this.....